A Health Care Personnel Guide For Assessing Radiation Risk And Selecting Imaging Procedures In Pregnant Women Easy-print edition of this Guide

This reference material is for use by medical staff affiliated with Brigham and Women's Hospital only. It is designed to inform your decision-making as you determine individual risks associated with medical imaging and communicate with your patients. It should not be interpreted as medical advice, nor is it necessarily germane to institutions using other imaging protocols. Patients with questions regarding these issues should speak directly with their caregivers. An additional resource is the Ask the Experts-Pregnancy and Radiation module of the Health Physics Society: http://www.hps.org
Diagnostic Exposure to the Fetus

To determine the radiation dose to the fetus, the cumulative radiation exposure from all the radiation exams the patient receives needs to be totaled.

Potential radiation effects are proportional to the tissues exposed, either directly or indirectly by the radiation. This means a x-ray beam that includes the fetal site, or substantial scattered radiation from a site near the fetus, produces the greatest dose.3

Diagram: Direct and scattered x-rays reach the conceptus 4

Diagram:Few scattered x-rays reach the conceptus 4

The following tables list mean fetal radiation exposures for single x-ray, CT, and nuclear medicine procedures at Brigham and Women's Hospital, as well as the fetal risk category as described in Table I.

Please keep in mind the following:

  1. These are average doses estimated from a heterogenous range of patients.
  2. Multiple exams result in an additive or cumulative dose.
  3. For patient-specific dose estimates or additional information, please contact Radiology Physics (x-ray procedures) at 617-732-7201 or Health Physics and Radiopharmacology (nuclear medicine procedures) at 617-732-6057.

The radiation dose, as defined with other terms in the Glossary, may be expressed with either conventional or international (SI) units. In this guide the fetal doses are expressed in SI units.

Table 2: Estimated Dose to the Fetus During Selected Radiographic Exams
Exam
BWH Fetal Dose (mGy)
Fetal Risk Category
Dental
<0.0001
I
Skull (3 views)
<0.0001
I
C-Spine (trauma series)
<0.0001
I
Shoulder (AP, LAT)
<0.0001
I
Chest (PA, LAT)
<0.0001
I
Femur (AP)
<0.0001
I
Femur (LAT)
<0.0001
I
Thoracic Spine (AP)
0.0008
I
Thoracic Spine (LAT)
0.0008
I
Cardiac Catheterization
0.074
I
Hip (LAT)
0.42
I
KUB (LAT)
0.43
I
Lumbar Spine (LAT)
0.59
I
Hip (AP)
0.63
I
Pelvis (AP)
0.93
I
Lumbar Spine (AP)
1.36
I
Upper GI series
1.75
I
KUB (AP)
2.08
I
ERCP
3.1
I
Pulmonary Angiogram
3.00-7.00
I
Intravenous Urogram (IVU)
37.0
I
Table 3: Estimated Dose to the Fetus During Selected CT Exams
Exam
Fetal Dose (mGy)
Fetal Risk Category
Chest
0.062
I
Pulmonary Embolism
lungs only
0.062
I
lungs and pelvis
0.211
I
Abdomen
1.4
I
Pelvis
15.4
I
Ureter
15.4
I
Urography
unenhanced
1.4
I
nephrographic
15.4
I
pyelographic
15.4
I
Total
32.2
I

In nuclear medicine studies, fetal radiation exposure is a function of: 1) the tracer's ability to cross the placental barrier; 2) concentrate in fetal tissue; or 3) the result of radiation emanating from a nearby organ, e.g., the urinary bladder5.

Please also note that certain radionuclides can be expressed in breast milk. Nursing mothers should consult with the nuclear medicine physician.

Diagram: Gamma rays from the bladder are primary contributors to conceptus irradiation 4

Diagram: 99mTc-sulfur colloid liver-spleen scan. Negligible radiopharmaceutical localization near uterus 4

Diagram: After 8 weeks postconception, radioactive iodine crosses placenta and concentrates in fetal thyroid 4

 

Table 4: Estimated Dose to Fetus During Selected Nuclear Medicine Studies
Exam Agent
Mean admin'd dose (MBq)
Fetal Dose (mGy)*
Fetal Risk Catagory
Ventilation lung scan Xe-133 (gas)
740
0.02
I
Perfusion lung scan Tc-99m MAA
74
0.22
I
Myocardial perfusion Tc-99m MIBI
1110
1.30
I
Renal Scan Tc-99m MAG3
370
4.44
I
Bone Scan Tc-99m MDP
925
4.93
I
PET scan F-18 FDG
370
7.8
I
Myocardial perfusion Tc-99m tetrofosmin
1110
8.44
I
Myocardial viability T1-201 chloride
148
8.70
I
PET/CT scan F-18 FDG & CT
370
18.5
I
Gallium scan - infection Ga-67 citrate
185
38.0
I
Gallum scan - tumor Ga-67 citrate
370
76.0
I

* Assumes radiopharmaceutical is administered at the 3-month gestational age, while administration before or after 3 months post-conception results in a lesser fetal dose.

For a summary dose display of sample procedures, see the following chart:

Chart: Fetal Dose/Exam