A Health Care Personnel Guide For Assessing Radiation Risk And Selecting Imaging Procedures In Pregnant Women
Easy-print edition of this Guide
This reference material is for use by medical staff affiliated with Brigham and Women's Hospital only. It is designed to inform your decision-making as you determine individual risks associated with medical imaging and communicate with your patients. It should not be interpreted as medical advice, nor is it necessarily germane to institutions using other imaging protocols. Patients with questions regarding these issues should speak directly with their caregivers. An additional resource is the
Ask the Experts-Pregnancy and Radiation module of the Health Physics Society:
http://www.hps.org
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Diagnostic Exposure to the Fetus
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To determine the radiation dose to the fetus, the cumulative radiation exposure from all the radiation exams the patient receives needs to be totaled.
Potential radiation effects are proportional to the tissues exposed, either directly or indirectly by the radiation. This means a x-ray beam that includes the fetal site, or substantial scattered radiation from a site near the fetus, produces the greatest dose.3
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The following tables list mean fetal radiation exposures for single x-ray, CT, and nuclear medicine procedures at Brigham and Women's Hospital, as well as the fetal risk category as described in Table I.
Please keep in mind the following:
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These are average doses estimated from a heterogenous range of patients.
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Multiple exams result in an additive or cumulative dose.
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For patient-specific dose estimates or additional information, please contact Radiology Physics (x-ray procedures) at 617-732-7201 or Health Physics and Radiopharmacology (nuclear medicine procedures) at 617-732-6057.
The radiation dose, as defined with other terms in the Glossary, may be expressed with either conventional or international (SI) units. In this guide the fetal doses are expressed in SI units.
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Table 2: Estimated Dose to the Fetus During Selected Radiographic Exams
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Exam
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BWH Fetal Dose (mGy)
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Fetal Risk Category
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Dental
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<0.0001
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I
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Skull (3 views)
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<0.0001
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I
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C-Spine (trauma series)
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<0.0001
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I
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Shoulder (AP, LAT)
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<0.0001
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I
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Chest (PA, LAT)
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<0.0001
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I
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Femur (AP)
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<0.0001
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I
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Femur (LAT)
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<0.0001
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I
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Thoracic Spine (AP)
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0.0008
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I
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Thoracic Spine (LAT)
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0.0008
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I
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Cardiac Catheterization
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0.074
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I
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Hip (LAT)
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0.42
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I
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KUB (LAT)
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0.43
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I
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Lumbar Spine (LAT)
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0.59
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I
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Hip (AP)
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0.63
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I
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Pelvis (AP)
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0.93
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I
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Lumbar Spine (AP)
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1.36
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I
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Upper GI series
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1.75
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I
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KUB (AP)
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2.08
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I
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ERCP
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3.1
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I
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Pulmonary Angiogram
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3.00-7.00
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I
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Intravenous Urogram (IVU)
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37.0
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I
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Table 3: Estimated Dose to the Fetus During Selected CT Exams
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Exam
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Fetal Dose (mGy)
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Fetal Risk Category
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Chest
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0.062
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I
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Pulmonary Embolism
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lungs only
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0.062
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I
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lungs and pelvis
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0.211
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I
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Abdomen
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1.4
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I
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Pelvis
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15.4
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I
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Ureter
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15.4
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I
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Urography
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unenhanced
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1.4
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I
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nephrographic
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15.4
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I
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pyelographic
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15.4
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I
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Total
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32.2
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I
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In nuclear medicine studies, fetal radiation exposure is a function of: 1) the tracer's ability to cross the placental barrier; 2) concentrate in fetal tissue; or 3) the result of radiation emanating from a nearby organ, e.g., the urinary bladder5.
Please also note that certain radionuclides can be expressed in breast milk. Nursing mothers should consult with the nuclear medicine physician.
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Table 4: Estimated Dose to Fetus During Selected Nuclear Medicine Studies
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Exam
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Agent
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Mean admin'd dose (MBq)
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Fetal Dose (mGy)*
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Fetal Risk Catagory
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Ventilation lung scan
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Xe-133 (gas)
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740
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0.02
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I
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Perfusion lung scan
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Tc-99m MAA
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74
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0.22
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I
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Myocardial perfusion
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Tc-99m MIBI
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1110
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1.30
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I
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Renal Scan
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Tc-99m MAG3
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370
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4.44
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I
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Bone Scan
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Tc-99m MDP
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925
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4.93
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I
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PET scan
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F-18 FDG
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370
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7.8
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I
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Myocardial perfusion
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Tc-99m tetrofosmin
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1110
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8.44
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I
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Myocardial viability
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T1-201 chloride
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148
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8.70
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I
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PET/CT scan
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F-18 FDG & CT
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370
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18.5
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I
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Gallium scan - infection
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Ga-67 citrate
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185
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38.0
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I
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Gallum scan - tumor
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Ga-67 citrate
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370
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76.0
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I
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* Assumes radiopharmaceutical is administered at the 3-month gestational age, while administration before or after 3 months post-conception results in a lesser fetal dose.
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For a summary dose display of sample procedures, see the following chart:
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