Multi-Vessel Diseases

Left Main Disease

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Impression:

  • Moderate-to-severe ischemia in anterior septum, anterior wall, and lateral wall from base to apex, including the apex (small lines) (13/25 segments, more than 50% of the total myocardial volume).

  • The ischemia involves both LAD and LCX territories, strongly suggestive of left main disease.

  • Mild increased RV uptake at rest, marked increase in RV uptake during stress.

    Coronary Angiography:

  • LM - at least 40% stenosis in a very thin LM
  • Otherwise diffuse CAD

    Echocardiography:

  • Left ventricular cavity size is normal with preserved systolic function
  • Left ventricular ejection fraction - 60%
  • Right ventricular enlargement with preserved right heart function

    Follow up:

  • The patient subsequently underwent LM single-vessel bypass (unusual for heart transplant patients)
  • Myocardial perfusion study three months after bypass was within normal limits

    Comments:
    It is not the degree of stenosis that determines the functional significance of any given stenosis -- but the flow capacity of the stenotics. This principle is clearly demonstrated in this patient.

    There is evidence of reinnervation (chronotrope response and chest pain) 10 years after transplantation.


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    Atlas of Myocardial Perfusion SPECT
    © Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

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    Initiated: Nov 19, 1995. Last updated: April 26, 1999.